Tolerance for psilocybin doses lasts for three weeks and tapers off slowly if no additional mushrooms are consumed. The rule of thumb with tolerance is that if you take 1g today you’ll need 2g tomorrow to get the same effect. On day 1 after dosing mushrooms your potency is 100% of your prior dose. At day 21 following a dose of psilocybin your tolerance will return to 0% as long as no additional mushrooms were consumed. For example, if you consume a gram of mushrooms on day one, you will need 2 grams of mushrooms on day two to reach the same experiential dose of psilocybin.
