Appendices

Drugs and Mysticism

Appendices A-G

Appendix

Appendix A

Medical History Form for Volunteer Subjects

Section I. Have you ever had any of the following?

Yes No
Yes No
Yes No
Yes No

Section II. Substance use history

Yes No

Section III. Psychotherapy history

Yes No
Yes No
Yes No

If yes, please explain in detail (symptoms, length and number of hospitalizations, treatment):

Yes No

Section IV. Allergic reactions

Yes No

Appendix B

Pre-Drug Experience Questionnaire1

Family history:

Religious background:

Indicate your theological position on the following continuum:

Orthodox ________ Neo-orthodox ________ Liberal

1 This was administered about three weeks before the experiment and reviewed during first interview.

How meaningful is the usual worship of your public religious life to you?

unmeaningful , slightly meaningful , very meaningful sometimes , very meaningful usually

If so, describe briefly:

Have you ever had any mystical or religious experience in the presence of nature? If so, describe briefly:

Have you ever had an experience in which you felt that you transcended time and/or space? (If yes, circle which) Describe briefly:

Have you ever had an intuitive experience of a sense of Presence of the Divine? If so, describe briefly:

Have you ever experienced a feeling of mystical union to any degree? If so, describe briefly:

Have you ever had an experience in which you felt that the Numinous was made near to you? If so, describe briefly:

Have any of your religious experiences given you a feeling of joy, blessedness, or peace in the Biblical sense of the peace that passes all understanding?

Have you had this experience in ways or circumstances that you would not consider religious?

Do you practice any spiritual exercises such as:

In a specific sense in which you felt overpoweringly guilty about a particular wrong deed or attitude?

Appendix C

Post-Drug Questionnaire with Significance Levels of the Difference Between Scores of Experimentals and Controls1

Please evaluate the following items in regard to your own experience in the psilocybin experiment. Rate each descriptive unit according to the following scale:

0 – did not experience at all

1 – cannot decide whether I experienced this or not

2 – experienced slightly

3 – experienced moderately

4 – experienced strongly

Note: Please reserve the highest rating (4) for a qualitative level which would equal or excel any previous personal experience or expectation which you would consider strong of these states. Feel free to make any further comments on any item in order to clarify your response.

1 Probabilities that the difference was due to chance are listed for each item. The Sign Test was used and the prediction was made that the scores of experimentals would be higher than of controls unless otherwise indicated.

  1. Seeing symbolic meanings of things (.18)
  2. Feeling of unity with your group (.64)
  3. Sense of the preciousness of life .02
  4. Feeling of being very wise, knowing everything (.23)
  5. Terror or fear .004
  6. Sense of finitude (.23)
  7. Sense of wonder .004
  8. Panic .016
  9. Loss of self .001
  10. Easy understanding of the feelings of others (.5)
  11. Concern and preoccupation with other people coming and leaving the room (.64)
  12. Being able to operate on several levels at once .004
  13. Sense of humility (.35)
  14. Sense of well being (.38)
  15. Fear of losing control .004
  16. Seeing a light which appeared to have no naturally explainable source .016
  17. Feeling that you were going to die during the experience (.063)
  18. Sense of having known the universe in its wholeness .016
  19. General sense of sin (.5)
  20. Conviction of certain specific sins in your life (.50)
  21. Sense of forgiveness or cleansing (.35)
  22. Sense of loneliness or aloneness .02
  23. Sense of ultimate goodness as the basis of reality .035
  24. Intuitive knowledge of your immortality (.11)
  25. Sense of judgment on your life (.78)
  26. Appearance of various levels of consciousness .001
  27. Suddenness of appearance of various levels of consciousness .002
  28. Suddenness of disappearance of various levels of consciousness .004
  29. Stability of level of consciousness during the experience .035 (for controls)
  30. Transiency of duration of deepest levels .002
  31. Transiency of duration of levels other than the deepest .004
  32. Permanence of new levels of consciousness after the experience (.062)
  33. Sense of certainty or conviction of encounter with ultimate reality (in the sense of being able to “know” and “see” what is really real) at the time of the experience .020
  34. Sense of certainty or conviction of encounter with ultimate reality now (in looking back) (.062)
  35. Sense that what was encountered was not real at the time of the experience (.5)
  36. Sense that what was encountered was not real now (in looking back) (.5)
  37. Intensity of the response to ultimate reality .004
  38. Totality of the response to ultimate reality .016
  39. Exaltation .020
  40. Depression (.09)
  41. Love .035
  42. Hate (.35)
  43. Tenderness (.66)
  44. Exuberance .002
  45. Meanness

    This basic characteristic may be described directly, or the response may take various forms. The experiencer may be moved with awe, wonder, humility, or a hushed reverent feeling. Spontaneous acts such as prayer or kneeling may be evoked. Other examples of this non-rational, intuitive response may include a sense of: finitude in contrast to the infinite; humility before the overpowering majesty of that which uniquely transcends the finite; the “wholly other”-ness of what is felt to be holy or divine; a mysterious fascination in spite of a feeling of awe, fear, or terror in the sense of a shaking or trembling in the innermost depths of one’s being; the urgency or energy of the holy or divine. As indicated, fear or terror may be part of the experience of sacredness, but certainly also can be experienced in a quite unrelated way. Do not score fear under this category, if not related.

    The use of religious terminology to describe the experience is another indication of sacredness. For example, the response may be interpreted by the experiencer as a sense of Divine Presence, the consciousness of a Beyond or More, the awareness of some cosmic Principle or Universal Self, or more specifically as the presence of Christ, God, or some other deity. Sacredness may be strongly felt, however, without any of these interpretations being given.

    Feelings of joy, love, or peace (of the previous category) may be evoked with a response of sacredness. Such an interconnection of these two categories should be watched for, but both categories should only be scored when there is clear indication that elements of both are present. However, they do not necessarily occur together.

    Scoring level is based on intensity of the basic response in any of the possible forms. Intensity may be judged from the tone, manner of description, and context.

    3 The profound sacredness of this level may include the high value and significance which the person places on his experience. The impact is shaking and very inspiring. Breathless awe may also accompany this level.

    2 The profundity and extreme character of 3 is lacking, but the sacredness is still impressive.

    1 Sacredness is definitely present, but weakly felt, i.e., not outstanding.

    IV. Unity

    The category of unity is divided into internal and external types, which are different ways of experiencing an undifferentiated unity. The major difference is that the internal type finds unity through an “inner world” within the experiencer, and the external type finds unity through the external world outside the experiencer. Both types may be experienced by the same person.

    Internal Unity

    The essential elements of unity experienced by turning inward are: loss of usual sense impressions, and loss of self without becoming unconscious. The multiplicity of usual external and internal sense impressions (including time and space), and the empirical ego or usual sense of individuality, fade or melt away, while consciousness remains. In the most complete experience, this consciousness is a pure internal awareness beyond empirical content, with no external or internal distinctions. One is not unconscious, however, but rather very much aware of an “inner world” of undifferentiated unity.

    These essential elements are described in terms of paradox. In spite of loss of sense impressions and dissolution of usual personal identity or self, the “I” still experiences the awareness of oneness or unity. The unity itself may be described as empty, yet full and complete. Either or both sides of this paradox may be emphasized by the various expressions used. On the one side, for example, the feeling of oneness with an empty unity expresses an awareness of the loss of sense impressions and may be indicated by such words as emptiness, void, abyss, wayless, unorganized, darkness, dissolution, or pure self. On the other side, the feeling of oneness with what is all-encompassing or greater than the usual self may be expressed by such words as fullness, completeness, pure being, or unity with the whole. These various expressions of the essential elements are evidence of the internal type of unity. Of course, the context must be considered.

    Watch for associated experiences which may alert you to these essential elements. Some examples are: expansion of consciousness to other dimensions within the self; experience of another “world” of reality different from the ordinary; or consciousness of an underlying cosmic Principle, Beyond or More, Universal Self, Logos, Christ, or God. However, for internal unity to be scored, such experiences must have additional clear indication of the loss of sense impressions or self with retention of awareness (e.g., unity, bond, or absorption with the particular example or additional description with some of the expressions used above).

    Scoring level is based on completeness:

    3 A strong degree of completeness means that there is loss of the multiplicity of all sense impressions and complete loss of self. A pure awareness of an undifferentiated unity is present beyond empirical content with no internal or external distinctions. In fact, internal and external lose their meaning. Time and space are completely transcended.

    2 A moderate degree of completeness means that internal distinctions remain. Although all external sense impressions and the usual sense of self are lost, internal imagery continues. Oneness is not complete.

    1 There is definite evidence of the essential elements, but not in as complete a way as in level 2. Sense impressions are lost, but only partially. There is only incomplete loss of the sense of self. Some awareness of the external environment remains.

    External Unity

    In this sub-category, unity is perceived outwardly with the physical senses through the external world. A sense of underlying oneness is felt behind the empirical multiplicity. The observer or subject feels that the usual separation between himself and an external object (inanimate or animate) is no longer present in a basic sense, yet the subject still knows that his individuality is retained. In spite of the empirical multiplicity of objects, which are still perceived as separate, the subject-object dichotomy is nevertheless in a paradoxical sense dissolved. On one level, the objects are separate, yet on another they are, at the same time, one with the subject. Another way of expressing this same phenomenon is that the essences of objects are experienced intuitively and felt to be the same at the deepest level. The subject feels a sense of oneness with these objects, because he “sees” that at the most basic level all are a part of the same undifferentiated unity. This oneness may be felt through things or people.

    Such external unity may also come as a deeply felt awareness of the life or living presence in things. There may be the realization that nothing is “really dead.”

    Watch for associated elements such as expansion of consciousness beyond the usual sense of self or consciousness of a Beyond or More, some cosmic Principle, etc. Such associated elements may point to more specific evidence of oneness or unity through external things. Completeness of associated loss of time varies, but transcendence of space is only partial or paradoxical, because external objects seem both separate and yet not separate.

    Scoring level is based on completeness:

    3 At this most complete level, the oneness has both depth and breadth. The capsule statement, “All is One,” emphasizes the broad dimension of this underlying unity in all things. A cosmic dimension is felt.

    2 The depth of oneness through things or people is present, but not the same wide scope of underlying unity in everything as in the most complete experience. The loss of usual separation between subject and object is limited to the immediate rather than cosmic dimension.

    1 Oneness, kinship, friendship is felt with unusual closeness, but the depth of oneness is not so complete as in level 2.

    V. Transiency of Unity

    Transiency means non-permanence of duration, i.e., loss of the phenomena of internal or external unity after, or perhaps even before, the whole experience is over. The duration of unity during the experience may last from seconds to hours, and the completeness may vary. Disappearance may seem gradual because of the afterglow effect, but transiency means that unity is not continuously sustained when the experience is over. Watch for indications that the essential elements are no longer present, e.g., mentions of “coming out” or “back to normal.”

    Scoring level is based on the intensity of the contrast between the degree of unity experienced during and afterwards:

    3 A strong intensity of contrast means that although there may be a re-living in memory and persisting changes in other ways, the actual experience of unity does not continue in the ongoing life of the experiencer. Even a moderate or slight degree of unity can produce a strong contrast in comparison to usual consciousness.

    2 A moderate intensity of contrast means that some of the actual phenomena of unity persist after the experience as a part of regular consciousness (even after 5 months), although perhaps in a lower degree of completeness.

    1 A low intensity of contrast means that much of the actual phenomena of unity persists at the same level of completeness as during the experience as a part of regular consciousness.

    0 No contrast means that the level of unity experienced continues unchanged afterwards. Of course, if none of the phenomena of unity was experienced at all, transiency also would be scored as 0.

    VI. Objectivity or Reality

    This category has two interrelated elements: (1) insightful knowledge or illumination which is felt at an intuitive, non-rational level and gained by direct experience, and (2) the authoritativeness or the certainty for the experiencer that such knowledge is truly or ultimately real, in contrast to the feeling that the experience was a subjective delusion. These two elements are connected because the knowledge through participation in ultimate reality (in the sense of being able to “know” and “see” what is really real), carries its own sense of certainty. Two kinds of reality must be distinguished in reading the accounts: (a) “ordinary” reality (the reality of usual, everyday consciousness), and (b) “ultimate” reality (awareness of another dimension not the same as “ordinary” reality but still quite “real” to the experiencer). In fact, “ultimate” reality may be judged to be more profoundly real than “ordinary” reality. In each individual case, the context must determine which type of reality is being mentioned or described.

    Such insightful knowledge does not necessarily mean an increase in facts, but rather intuitive illumination. What becomes “known” (rather than intellectually assented to) is intuitively felt to be authoritative and requires no proof at a rational level, and has an inward feeling of objective truth. The content of this knowledge can be divided into two main types: insights into being and existence in general, and insights into one’s personal, finite self. The certainty of the reality and significance of the content applies to both. Examples of insights about being and existence in general are the direct realization through the present experience of hitherto undreamed-of realities and possibilities of experience, new perspectives on old facts or ideas, new understanding of relationships and meanings, new appreciation of the universe as a whole, or an experience of “everything falling into place.” Examples of insights about one’s personal self are: a new certainty about vocational choice; realization of faults or problems to be met; understanding of the causes of conflict; or a clear vision of one’s true self without self-deception. Such personal insights are at a level different from “ordinary” everyday reality.

    Scoring level is based on the intensity of the certainty for the experiencer that the insightful knowledge gained is of “ultimate” reality (i.e., really real and not a delusion):

    3 The characteristic of this level is the profundity of the conviction that “ultimate” reality has been encountered. The insightful knowledge is felt to be profoundly significant and true. The response to ultimate reality is total, and there is a feeling of being totally grasped and dealt with. There is no doubt that what is experienced and known is truly or ultimately real, and this conviction persists after the actual experience is over (even after 5 months).

    2 The totalness and profundity of the certainty is lacking. There is some doubt as to the “ultimate” or true reality of the insights gained. Degree of certainty may decrease after the experience.

    1 Insights are present, but at a less intense level of certainty of their “ultimate” reality than in 2. There is serious doubt as to their reality, but some conviction of reality remains, although it may be on the wane.

    VII. Paradoxicality

    Any use of paradoxical language in describing or interpreting the experience or its meaning should be scored in this category. Paradoxical language is defined as language which is logically contradictory in statements about, descriptions of, or interpretations of the experience. Examples may include the experience of an empty, yet full and complete unity, the paradoxical loss of the sense of self and dissolution of individuality with retention of consciousness of what is experienced, or the separateness, yet unity with objects in the experience of external unity (paradoxical transcendence of space). Watch for descriptions of such paradoxical experiences.

    Degree of paradoxicality is to be scored on how paradoxical any examples found appear to the judge, i.e., based on degree of intensity:

    3 This level means that although obviously contrary to common sense, contradictory statements are still strongly stated as true descriptions of the experience. The examples are striking, and the account gives a strong impression of paradoxicality.

    2 Contradictory statements appear only moderately paradoxical. The striking element is lacking.

    1 Paradoxicality is present, but only to a low degree. The examples are not particularly impressive.

    VIII. Alleged Ineffability

    This category is for any mention or indication of difficulty in adequately describing one’s own experience in words. Watch for comparisons with the person’s previous ease or difficulty in describing his personal experiences. The tone of the whole account is important in judging this category.

    Scoring level is based on the intensity of the indication of difficulty of description.

    3 This level designates direct statements made with conviction that the experience is beyond words and verbal description.

    2 This level reflects direct statements of ineffability which are made without the emphasis of level 3, or strong indirect indications from the account in general.

    1 Statements give an impression of ineffability, but only weakly.

    IX. Persisting Changes in Attitude and/or Behavior after Six Months

    This category is for any persisting changes, positive or negative, in attitude and/or behavior which are a result of the experience. These changes are divided into sub-categories according to type of change, whether positive or negative. Phenomena occurring during the actual experience are not included, only their continuing effects in the life of the experiencer. Watch for changes occurring during the experience, or by the time of the initial writeup, and see if they are still present six months later.

    The positive changes are divided into 4 main groups: (A) toward self, (B) toward others, (C) toward life, (D) toward the experience itself.

    (A) Increased integration of personality is the basic inward change in the personal self. Such integration in the form of a reorganization of the personality and growth in maturity, may have developed relatively rapidly or slowly as a result of what occurred during the experience. (For example, from a radical experience of death and rebirth, or conversion, or as an effect of insight which was gained in the depth of the experience and gradually utilized later.) Undesirable traits may be faced in a way that they can be dealt with and finally reduced or eliminated. Issuing from personal integration, the sense of one’s inner authority may be strengthened, and the vigor and dynamic quality of life may be increased. Creativity and greater achievement-efficiency may be released. There may be an inner optimistic tone with consequent increase in feelings of happiness, joy, and peace.

    (B) Change in attitude and behavior toward others includes more sensitivity, more tolerance, more real love, and more authenticity as a person by being more open and more one’s true self with others. The response of others is a good indication of such changes, if mentioned.

    (C) Positive change in life-attitude or goal may include philosophy of life, sense of values, sense of meaning, purpose in life, vocational commitment, need for service to others, and new appreciation for life or the whole of creation. Life may seem richer. The sense of reverence may be increased, and more time may be spent in devotional life and meditation.

    (D) Positive attitude toward the experience means that it is regarded as valuable and that what has been learned is thought to be useful. The experience is remembered as a high point, and an attempt is made to recapture the experience or, if possible, to gain new experiences as a source of growth and strength. Mystical experiences of others are more appreciated and understood.

    Negative changes are divided into the same four groups and include the negative counterparts of the positive elements mentioned above. (A) Personal disintegration is the basic change toward self and includes fear, anxiety, insecurity, loneliness, depression, despair, mental confusion, delusion, feeling of “unreality,” regression in maturity, less dynamic quality and vigor, unhappiness, turmoil, inner pessimism. (B) Negative changes toward others include less effective interpersonal relations, withdrawal into self, friction, antagonism, hatred, less sensitivity, less tolerance, and less authenticity as a person. (C) Negative changes toward life may include a cynical and bitter attitude and less intensity in or loss of the positive items listed above under this sub-category. (D) Negative changes toward the experience include regret for participation and attempts to forget and suppress the experience, which may be regarded as harmful.

    Scoring level is based on intensity of benefit or harmfulness. Decide to which sub-category each item of the six-month followup data belongs. Then score each sub-category according to the intensity communicated by the account.

    3 This level means that the person feels strong or very strong benefit or harm.

    2 This level indicates moderate benefit or harm.

    1 This level indicates slight or questionable benefit or harm.

    With the above categories in mind, read all the accounts through in succession, at one sitting.

    Working on the accounts one at a time, in order:

    a. Read the first account straight through to get the general feel and tone. Feel free to mark in the margin in pencil, with the major category numbers (I to IX) any sentence which impresses you at the time as an obvious example of a particular category. Don’t worry at this point about scoring intensity or completeness. Read to get an impression of the account as a whole.

    b. Using the score sheet, read the account through and look for examples of category I (transcendence of time and/or space). Mark them with the category number. Then give a qualitative rating (0 to 3) for each scoring division of this category, as indicated on the score sheet. Base your score on the highest level reached at any point in the experience. Thus an element mentioned only once may have been described in such a way as to indicate a 3-level experience. Rate on the basis of the highest level for an essential element of a particular scoring division, in accordance with the description of the category. Be sure to rate the experience of the person writing the account, not his description of what other people were experiencing.

    c. Then read the same account through again and mark examples of categories II and III (positive mood and sense of sacredness). Score these items on the score sheet in the appropriate place. Follow this same procedure for the rest of the categories. Look for evidence of categories IV and V at one reading. Categories VII and VIII may also be combined in this way.

    d. When you have finished the first account, do the same for each of the remaining ones, in order. Try to finish two accounts at least at one sitting.

    Content Analysis Score Sheet Used by Judges
    with the Probability for each Item that the Difference between Experimentals and Controls was due to Chance1

    I. Transcendence of time or spacep values (for Experimentals)
    (1)Loss of usual sense of time.001
    (2)Loss of usual sense of space.001
    II. Positive mood
    (3)Joy.002
    (4)Love.035
    (5)Peace or blessedness(.063)
    III. Sense of sacredness(.37)
    (6)
    IV. Unity
    (7)Internal unity.002
    External unity
    (8)Oneness through external objects other than people(.25)
    (9)Oneness through people.032
    V. Transiency of unity
    (10).004
    VI. Objectivity and reality
    (11)Insights into being and existence in general.004
    (12)Insights into personal finite self(.11)
    VII. Paradoxicality
    (13).001
    VIII. Ineffability
    (14).008
    IX. Persisting changes in attitude or behavior six months later
    Positive:Negative:
    (15)Toward self .004(16) (.13)
    (17)Toward others (.50)(18) (1)
    (19)Toward life .016(20) (1)
    (21)Toward the experience (.19)(22) (.25)

    1 The Sign Test was used to calculate p values from judges’ scores.

    Reliability of Judges as Determined from Kendall Rank Correlation Coefficient (W)1

    1 Siegel, op. cit., pp. 213-223.

    Appendix F

    EXPLANATION OF THE COLUMNS AND SYMBOLS USED IN THE CATEGORY TABLES

    Items(a) Subject groupFrequency of Distribution (Number of times scored) (10 subjects)Total ScoreSign Test statistics
    (n= 10) (b)Strong Moder. Slight None (c)Actual Maximum (d)N e (e)

    (a) The items which were combined from either the post-drug, follow-up, or content-analysis data.

    (b) The group of subjects, either 10 experimentals or 10 controls.

    (c) Frequency distribution shows the total number of responses made by all experimentals and controls at the particular scoring level indicated. The scoring scales on the three methods of measurement were correlated for easy comparison (i.e., the “strong” level for each rating scale was not the same numerical value. This level represented a score of “three” on the content-analysis scale, “four” on the post-drug questionnaire scale, and both “four” and “five” on the follow-up questionnaire scale. The “slight” level represented a score of “one” on the content-analysis scale, and both “one” and “two” on the questionnaire scales).

    (d) The sum of the weighted scores at each level. Maximum is the sum which would have been obtained if all the subjects scored all the items at the highest possible level.

    (e) N = number of matched pairs with a difference in score when the score of the control subject was subtracted from the score of the experimental subject. The prediction had been made that the experimental score would be higher. The maximum value of N = 10.
    p = the probability that the predicted higher scores of the experimentals were due to chance.

    Appendix G

    DATA NOT DIRECTLY RELEVANT TO CATEGORIES OF THE TYPOLOGY OF MYSTICISM

    Group I: Integrative and Constructive Phenomena

    p values (for experimentals)

    Phenomena which occurred during experience:

    Using all scores:Using only “strong” scores:
    Post-drug data:
    P3 Sense of the preciousness of life:.020.032

    Follow-up data:

    Phenomena which occurred within a few days after the experience (all from post-drug data):

    P88bDeath experience:(.063)(.25)
    P84bIncreased integration of personality:(.090)(.063)
    P92bFelt need for some type of service to others:(.18)(.18)
    P89bRebirth experience:(.19)(.19)
    P93bActual changes in behavior in ways you would consider constructive and positive:(.18)(.18)
    P95bConversion experience:(.19)(.19)

    Group II: Disturbing Changes in Attitude and Behavior

    p values (for experimentals)

    Phenomena which occurred during experience (all from post-drug data):

    Using all scores:Using only “strong” scores:
    (1) Fear and Anxiety:
    Melancholia:
    Disorientation:
    Antisocial Feelings or Behavior:

    Phenomena which occurred within a few days after the experience (all from post-drug data):

    Phenomena which occurred within six months after the experience:

    (See Part III of Follow-Up Questionnaire in Appendix D for the remaining negative items, none of which proved significant,p greater than .1).

    Group III: Physical Sensations

    p values (for experimentals)

    Using all scores:Using only “strong” scores:
    P104 Colors more intense:.001.008
    P105 Visions of colors, geometric

    (See items P100-P115 on post-drug questionnaire in Appendix C,for items above .1 level.)

    Group IV: Miscellaneous

    Post-drug data:

    P128 Got psilocybin:.001.001

    Follow-up data:

    F80b You place less importance on traditional theological formulations to express spiritual insights:.035(.25)
    F100a You are convinced you had psilocybin:.001.001
    F100b …did not have psilocybin:.001 (for controls).001

Source: Walter Norman Pahnke, Drugs and Mysticism: An Analysis of the Relationship between Psychedelic Drugs and the Mystical Consciousness, Ph.D. thesis, Harvard University, June 1963. Download original PDF. Digitally restored from the original typescript. OCR conversion by Adobe Acrobat; text correction and HTML formatting by AI restoration pipeline. Published here by the Church of Ambrosia as a primary historical document.